Innovative Methodology A self-calibrating telemetry system for measurement of ventricular pressure-volume relations in conscious, freely moving rats
نویسندگان
چکیده
Kazunori Uemura, Toru Kawada, Masaru Sugimachi, Can Zheng, Koji Kashihara, Takayuki Sato, and Kenji Sunagawa Department of Cardiovascular Dynamics, National Cardiovascular Center Research Institute, Suita 565-8565; Japan Space Forum, Tokyo 105-0013; Organization of Pharmaceutical Safety and Research, Tokyo 100-0013; and Department of Cardiovascular Control, Kochi Medical School, Nankoku 783-8505, Japan
منابع مشابه
A self-calibrating telemetry system for measurement of ventricular pressure-volume relations in conscious, freely moving rats.
Using Bluetooth wireless technology, we developed an implantable telemetry system for measurement of the left ventricular pressure-volume relation in conscious, freely moving rats. The telemetry system consisted of a pressure-conductance catheter (1.8-Fr) connected to a small (14-g) fully implantable signal transmitter. To make the system fully telemetric, calibrations such as blood resistivity...
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Measurements of left ventricular pressure (LVP) in conscious freely moving animals are uncommon, yet could offer considerable opportunity for understanding cardiovascular disease progression and treatment. The aim of this study was to develop surgical methods and validate the measurements of a new high-fidelity, solid-state pressure-sensor telemetry device for chronically measuring LVP and dP/d...
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تاریخ انتشار 2004